The individual components of Total Calm & Focus™ have been extensively evaluated in many animal studies. Magnolia extracts including honokiol and magnolol have been studied in comparison with diazepam. These studies found that honokiol had an anxiolytic effect without any of the common side effects of diazepam (motor dysfunction, sedation or amnesia).
Canopus BioPharma Inc has recently completed a Phase IV clinical trial to assess the anxiolytic effects of Total Calm & Focus™. This randomised, placebo controlled study of biological and psychological effects was performed at Swinburne University of Technology in Australia. The main aim of this clinical study was to explore the beneficial effects of Canopus’s nutraceutical Total Calm & Focus™, an anxiolytic dietary supplement, on biological and psychological processes amongst a human population.
Forty participants were randomly allocated to either Total Calm & Focus™ or a placebo group. Participants self administered 2 capsules of Total Calm & Focus™ every morning for 14 days. They also completed a series of questionnaires over a 4-week period to assess daily stress, depression and anxiety, and daily incidences of health-related symptoms. Participants also provided saliva samples throughout the study period. Each saliva sample was analysed for the biological markers of stress, cortisol and alpha-amylase across the 4 daily time points.
Patients reported noticeable improvements in general mental health, Total Calm and Focus™ demonstrated a statistically significant reduction in cortisol and alpha-amylase levels in patients, alleviating the damaging physiological aspects of stress on the brain and other organs.
This study confirms the calming and stress reducing effects of the nutraceutical product Total Calm & Focus™, strengthening Canopus’ ability to market with proven clinical claims.
Safety Profile of Total Calm & Focus™
The active ingredients in Total Calm & Focus™ have been extensively tested with no negative side effects to date. Researchers have examined the effects of magnolia bark extract, the results of which further support the use of this in Total Calm & Focus™. Studies have found the following:
- No adverse effects
- No genotoxicty
- Safe for dietary consumption
- No mortality observed
- No toxic effects on clinical chemistry
- Does not cause chromosomal aberrations (DNA damage)
Will TotalCalm&Focus™ work for me?
Most people who take TotalCalm&Focus™ experience increased relaxation, a sense of well-being, and reduced worry within 30 minutes. The success rate of TotalCalm&Focus™ is extraordinarily high, with as many as 90% of users reporting positive results. Please keep in mind however, that every person is different and individual results will vary.
How quickly will TotalCalm&Focus™ take effect?
TotalCalm&Focus™ works in about 15 minutes on an empty stomach and about 30-60 minutes on a full stomach. According to our informal surveys, 69% of TotalCalm&Focus™ users report that, on average, TotalCalm&Focus™ begins working in less than 30 minutes after a single dose.
How long does a single dose continue working?
On average, TotalCalm&Focus™ effects last for 8-12 hours after a single dose. Of course, individual results vary, and some clients report that TotalCalm&Focus™ continues working for 16 hours or more.
Is TotalCalm&Focus™ a prescription medication?
No, TotalCalm&Focus™ is a natural supplement, not a drug. A prescription is not necessary to purchase TotalCalm&Focus™. (Keep in mind that TotalCalm&Focus™ should not be considered a replacement for FDA-approved medication or professional medical treatment.
Directions and Dosage
Should I take TotalCalm&Focus™ everyday or only "as needed"?
This depends on you. If you struggle with stress and anxiety or frequent panic attacks, you can use TotalCalm&Focus™ everyday for uninterrupted relief. On the other hand, if you experience occasional anxiety or infrequent panic attacks, you can take TotalCalm&Focus™ "as needed" to calm you down and lift you up when you need it most. TotalCalm&Focus™ achieves high success rate for all types of anxiety. For detailed information, read the Dosage and Directions for Use.
How many capsules should I take at once? How many times should I take TotalCalm&Focus™?
A single capsule is sufficient for most people, but in some cases, taking two capsules at once may be more effective. If one capsule a day is to strong, switch to one capsule every other day. For regular daily use, the recommended dose is one daily on an empty stomach. For occasional use, take one or two capsules "as needed". Do not exceed six capsules in one day. Please see the Dosage and Directions for Use for more information.
Safety
Can I take TotalCalm&Focus™ if I am currently taking a prescription anti-anxiety medication?
In general, TotalCalm&Focus™ can be safely combined with prescription sedatives, including benzodiazepines such as Valium® (diazepam), Xanax® (alprazolam), and Ativan® (lorazepam). Keep in mind that TotalCalm&Focus™ may increase the effects of sedative medications, although this interaction is not unsafe at recommended doses. If you are taking any type of sedative medication, use caution when driving or operating heavy machinery until you are familiar with the effects of TotalCalm&Focus™. Some clients report that TotalCalm&Focus™ potentiates anti-anxiety drugs in a positive way and allows them to obtain relief from a lower dose of medication. If you are currently taking prescription medication, it's always a good idea to talk to your doctor before taking TotalCalm&Focus™ or any new supplement.
Can I take TotalCalm&Focus™ if I am currently taking a prescription anti-depressant medication?
In general, TotalCalm&Focus™ can be safely combined with prescription SSRI antidepressants, including Celexa® (citalopram), Lexapro® (escitalopram), Luvox® (fluvoxamine), Paxil® (paroxetine), Prozac® (fluoxetine), and Zoloft® (sertraline), as well as non-SSRI reuptake inhibitors such as Effexor® (venlafaxine) and Wellbutrin® (bupropion). TotalCalm&Focus™ should not be combined with MAO inhibitors. If you are currently taking prescription medication, it's always a good idea to talk to your doctor before taking TotalCalm&Focus™ or any new supplement.
Is it safe to take TotalCalm&Focus™ while pregnant or nursing?
TotalCalm&Focus™ is safe for teenagers, but children under twelve (12) should not take TotalCalm&Focus™ (or any other supplement) without the supervision of a pediatrician. Teenagers under eighteen (18) years of age should take TotalCalm&Focus™ only with the consent and supervision of their parents or guardians.
Is it safe to consume alcohol while taking TotalCalm&Focus™?
Do not consume alcohol until you are familiar with the effects of TotalCalm&Focus™. In general, consumption of moderate amounts of alcohol is safe while taking TotalCalm&Focus™. TotalCalm&Focus™ may increase the sedative effects of alcohol, so avoid drinking large quantities of alcohol while taking TotalCalm&Focus™.
Can I take TotalCalm&Focus™ if I am already taking prescription medications?
Before taking TotalCalm&Focus™, talk your doctor if you are taking muscle relaxants, other sleep or anxiety medicines, pain medicines, seizure medicines, or other medicines that cause drowsiness. TotalCalm&Focus™ may increase the sedative effects of these drugs. Do not take TotalCalm&Focus™ if you are currently taking an MAOI. Consult your doctor before taking TotalCalm&Focus™ if you have a serious or potentially fatal medical condition.
Can I take TotalCalm&Focus™ with other vitamins or nutritional supplements?
Yes, it's safe to take TotalCalm&Focus™ if you are also taking other vitamins or nutritional supplements. Adding GABA and/or Taurine, amino acids that work immediately to promote feelings of relaxation and tranquility, may increase TotalCalm&Focus™ anti-anxiety effect.
Possible Side Effects
Will I experience side effects when taking TotalCalm&Focus™?
Most people taking TotalCalm&Focus™ report experiencing NO side effects. Moreover, of those users that do report side effects, nearly 4 out of 5 describe them as "mild".
What are the possible side effects?
You are unlikely to experience side effects when taking TotalCalm&Focus™. When side effects do occur, they tend to be mild and often disappear. The most common side effects include drowsiness, and headache. TotalCalm&Focus™ may increase the effects of sedative drugs.
Is TotalCalm&Focus™ addictive or habit-forming?
No, TotalCalm&Focus™ is not habit-forming when taken as directed. You do not have to worry about becoming dependent on TotalCalm&Focus™ if you take it regularly.
Will I experience withdraw symptoms if I stop taking TotalCalm&Focus™?
Unlike most anti-anxiety drugs, TotalCalm&Focus™ does not cause severe withdrawal symptoms when discontinued. You do not have to worry about experiencing the nasty effects of withdrawal if you decide to stop taking it.
Obtaining TotalCalm&Focus™
Where can I purchase TotalCalm&Focus™?
TotalCalm&Focus™ can be ordered online at totalcalm.net using Visa, MasterCard or American Express. Our secure servers will process your payment, and all your information will remain confidential.
Is it safe and secure to order TotalCalm&Focus™ online?
Yes, all online orders will be processed through our secure servers. The information that you submit with your order is encrypted to ensure that it remains safe, secure and private. For details, please read our Security and Privacy Policy.
Is TotalCalm&Focus™ sold in stores?
At this time, TotalCalm&Focus™ is not available in national retail chains. Some local or regional vitamin or health food stores may carry TotalCalm&Focus™. Try calling stores in your area to find out if TotalCalm&Focus™ can be purchased locally. For most people, the easiest way to obtain TotalCalm&Focus™ is to order online.
Can I get a free sample of TotalCalm&Focus™?
Canopus BioPharma Corporation does not provide free samples at this time. We price TotalCalm&Focus™ reasonably, so that both new customers and long-time users can purchase the supplement affordably. Unlike most natural supplements, which cost only a few dollars to manufacture, TotalCalm&Focus™ is quite expensive to produce because it contains pure premium herbal extracts. Distributing free samples would drive up the price of TotalCalm&Focus™, making it less affordable for the thousands of people that take it regularly. Because TotalCalm&Focus™ has a high success rate, we are confident that your experience with the supplement will be positive. Order today to find the serenity of TotalCalm&Focus™.
How much does TotalCalm&Focus™ cost?
TotalCalm&Focus™ costs far less than expensive prescriptions and even most other anti-anxiety supplements. TotalCalm&Focus™ unsurpassed success rate generates a large base of loyal customers, which, despite its high production cost, allows us to price TotalCalm&Focus™ below competing products.) Moreover, three and six-month quantities are sold at significant discounts to ensure that long-term users can purchase TotalCalm&Focus™ affordably.
Can I pay with credit card, debit card, check or money order?
Yes, you can pay online with Visa, MasterCard or American Express. Your online payment will be processed by our secure servers to ensure that all information is kept safe and confidential.
Is TotalCalm&Focus™ available to customers outside the United States?
At this time we do not ship outside of the United states. We do plan in the near future to be able to ship TotalCalm&Focus™ to anywhere in the world. Simply order online with Visa, MasterCard or American Express. Be sure to follow the directions on the checkout page to select the appropriate shipping method.
What is the return policy?
Please read the Terms and Conditions of Sale before ordering to review return policy and procedure.
Do you ship to PO Boxes?
Yes, we do ship TotalCalm&Focus™ to PO boxes. All orders are sent USPS 2 to 3 day Priority Mail.
Once I order, how long will it take my TotalCalm&Focus™ to arrive?
Most orders are shipped the next business day. In the US, allow 2-3 business days for USPS Priority. At this time, we do not ship outside of the United States.
Quality Control
Trust TotalCalm&Focus™...potency assured through quality control.
TotalCalm&Focus™ contains only standardized plant extracts and powerful antioxidants to ensure consistent potency and purity.
The laboratory that produces TotalCalm&Focus™ conforms to or exceeds all Current Good Manufacturing Practices (cGMP). Canopus BioPharma uses manufacturing facilities that are perhaps the best for natural supplements in terms of quality-control and quality-assurance.
The quality of every bottle of TotalCalm&Focus™ is guaranteed by:
• Stringently scrutinizing and qualifying ingredient suppliers
• Quarantining all incoming raw materials immediately upon receipt
• Analyzing raw materials before releasing them to production
• Re-analyzing raw materials on a periodic schedule as required
• Conducting in-process inspections throughout manufacturing
• Testing for full compliance verification
• Visually inspecting every finished unit-dose
• Quarantining finished goods until quality-control chemists complete a final quality control review
• Retaining bottled samples of each production batch for future reference
These thorough quality-assurance procedures make TotalCalm&Focus™ a natural supplement that you can trust to deliver on its promises. Order TotalCalm&Focus™ today and wave your worries goodbye!
Safety
TotalCalm&Focus™ is safe and usually well tolerated. Most people who take TotalCalm&Focus™ do not experience side effects. When side effects do occur, they tend to be mild and often disappear.
You can safely take TotalCalm&Focus™ with all nutritional supplements and most prescription medications. Please review the list of drug interactions before taking TotalCalm&Focus™.
When taken as directed, TotalCalm&Focus™ is safe and poses no short-term or long-term health risks. Read the contraindications and precautions before taking TotalCalm&Focus™.
Feel free to contact TotalCalm&Focus™ Customer Support if you have any questions or concerns. We are here to help. Otherwise, you can order online for delivery direct to your doorstep.
"Your product works. I'm a student with problems focusing when I study. My mind wonders and its hard to concentrate and do well in school. Your product gave me the ability to concentrate and focus with greater retention and recall. I feel like I have a reservoir of mental energy because I can study for hours without getting tired. My work has improved with little effort. Thank you."
- Daniel... Laguna, CA
"I'm 52 years old and I feel great on TotalCalm&Focus. I live in Venice California working as an artist. Before taking your product I produced only a few paintings a month. I'm now producing four to five painting a week. My productivity is through the roof, because I can focus. The clarity is amazing. I feel like I am more creative and doing my best work. For me, your product defiantly has done what you claim it to."
- Danuta... Venice, CA
“I'm 82 years old. When I don't take our product I feel like it is time for me to go into an old age home. But when I take it I feel like going to dinner with friends, cleaning my home, and visiting my family. Thank you. This is the best I've felt in years.”
– Evelyn... Villanova, PA
“I feel great when I take your product. It puts me in a better mood. I feel like getting out of the house, even if it's just to go to the store. I call up friends and family and invite people to dinners.”
– Joan... Riverside, CA
“This product makes a big difference for me in my day to day life. I'm very focused and productive at work. And things that seemed so difficult before seem easy and without effort. And I don't feel any type of crash when I stop taking them. It's a great product and I recommend it to anyone who has trouble with focus or concentration.”
– Jeff... Denver CO
“I feel a huge relief in my life. I didn't know the lack of focus I've had all my life could be so stressful. I feel really good and it worked for my in just a couple of days. My boyfriend has also noticed and commented on the fact that I seem calmer and less stressed out by the little things in life. So, I have to say thank for this great feeling of confidence and contentment. It has been a wonderful thing for me to experience the relief that I believe taking these pills has given me.”
– Jessica... Los Angeles, CA